TR-Dewax-AR All-in-One Pre-Treatment
Deparaffinization, hydration and antigen retrieval in one 30-minute run. No xylene, no eight-step solvent ladder — a single 98°C bath replaces two hours of manual pre-treatment.
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Replace the Solvent Ladder With a Single 30-Minute Run
The same result the manual protocol produces, without the xylene, the graded ethanol series, or the 20–40 minute retrieval step.
TR-Dewax-AR Integrated Reagent
TR-Dewax-AR
One reagent bath performs all three pre-treatment steps. The slide goes in at 98°C and comes out ready for blocking and antibody incubation.
- Deparaffinization, hydration and antigen retrieval in a single step
- 30 minutes at 98°C, versus 100–120 minutes of solvent steps
- No xylene and no graded ethanol series
- Validated for IHC, ISH and IF workflows
The Manual Solvent Protocol
Conventional Protocol
Ten baths across two hours. Xylene for wax removal, four graded ethanol baths for hydration, then a separate retrieval step.
- Two xylene baths at 20 minutes each
- Two absolute ethanol baths at 10 minutes each
- Four graded ethanol baths at 5 minutes each
- Separate 20–40 minute antigen retrieval — 100–120 minutes total
Key Numbers
Where TR-Dewax-AR Fits
Routine IHC
Standard pre-treatment before chromogenic IHC, on the TR-Stainer or by hand.
Immunofluorescence
Pre-treatment for direct and indirect IF protocols, routine panels and research panels alike.
In-Situ Hybridization
Combined with hybridization steps for RNA and DNA target detection.
Multiplex mIF Panels
Uniform pre-treatment across every slide in a 30–40 marker panel, before cyclic staining.
Difficult Tissue Blocks
High-temperature retrieval that shortens the recovery step on hard, fatty or over-processed blocks.
Core Screening
Whole-slide pre-treatment for micro-array cores, with handling reduced to a single bath.
Works with the rest of the TerryDR stack
TR-ISE immunostain enhancer kit
Blocking buffer and antibody diluent that raise signal and cut background after pre-treatment.
TR-ASR antibody strip reagent
The strip step that clears bound antibodies between rounds of cyclic multiplex staining.
TR-Stainer automated IHC stainer
Microfluidic-chip-controlled incubation — 30 minutes for full IHC, no proprietary reagents required.
TerryDR spatial analysis software
Nine QuPath modules — preprocessing, registration, segmentation, phenotyping, and spatial statistics.
Cut pre-treatment from two hours to thirty minutes
We'll send the full protocol, reagent pricing, and a step-by-step comparison against your current workflow.